Unleash the potential of CRISPR with BTX Electroporation Systems
Your current CRISPR technology may be limiting the potential of your CRISPR applications. Electroporation has become the method of choice for CRISPR gene editing applications, quickly overtaking traditional methods such as chemical reagents or microinjection. |
BTX has been in the forefront of electroporation technology since introducing the first commercial electroporator in 1983. Our latest electroporation instruments are leading the charge for CRISPR gene editing applications! BTX Gemini and ECM 830 Electroporation Systems provide efficient, reproducible delivery of CRISPR/Cas 9, guide RNA, and homologous repair donor constructs to virtually any cell or tissue of interest. |
Gemini Twin Wave Universal Electroporation System |
These flexible twin wave systems allow both square wave and exponential decay wave electroporation in a single unit. Ideal for CRISPR and many other electroporation applications including, in vivo, in vitro, in ovo and more.
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ECM 830 Mammalian Transfection System |
This versatile square wave electroporation system is designed for gene, drug and protein delivery in mammalian cells and tissues, including CRISPR applications.
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Contact Us to request a quote or a free demo. | ||
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Selected References
Bhowmik, P., et al. Targeted mutagenesis in wheat microspores using CRISPR/Cas9. Scientific reports. 2018; 8.
Feng, W., et al. CRISPR-mediated Loss of Function Analysis in Cerebellar Granule Cells Using In Utero Electroporation-based Gene Transfer. J. Vis. Exp. 2018;136. doi: 10.3791/57311.
Kieper, SN, et al. Cas4 facilitates PAM-compatible spacer selection during CRISPR adaptation. Cell reports. 2018; 22(13):3377-3384.
Li, P., et al. Allele-specific CRISPR-Cas9 genome editing of the single-base P23H mutation for rhodopsin-associated dominant retinitis pigmentosa. The CRISPR Journal. 2018;1(1): 55-64.
Long, S, et al. CRISPR-mediated Tagging with BirA Allows Proximity Labeling in Toxoplasma gondii. Bio-protocol. 2018;8(6). pii: e2768. doi: 10.21769/BioProtoc.2768.
Sidik, SM, et al. CRISPR-Cas9-based genome-wide screening of Toxoplasma gondii. Nature protocols. 2018; 13(1):307.
Callif, BL, et al. The application of CRISPR technology to high content screening in primary neurons. Molecular and Cellular Neuroscience. 2017;80:170-179.
Liao, HK, et al. In vivo target gene activation via CRISPR/Cas9-mediated trans-epigenetic modulation. Cell. 2017; 171(7):1495-1507.
Yao X, et al. CRISPR/Cas9 - Mediated Precise Targeted Integration In Vivo Using a Double Cut Donor with Short Homology Arms. EBioMedicine. 2017;20:19-26.
Qin W, et al. Efficient CRISPR/Cas9-Mediated Genome Editing in Mice by Zygote Electroporation of Nuclease. Genetics. 2015;200:423-430.
Sidik S, et al. Efficient Genome Engineering of Toxoplasma gondii Using CRISPR/Cas9. PLoS ONE. 2014;9: e100450.
Wang X, et al. Efficient CRISPR/Cas9-Mediated Biallelic Gene Disruption and Site-Specific Knockin after Rapid Selection of Highly Active sgRNAs in Pigs. Sci Rep. 2015;5:13348.
Xie Z, et al. Optimization of a CRISPR/Cas9-Mediated Knock-In Strategy at the Porcine Rosa26 Locus in Porcine Foetal Fibroblasts. Sci Rep. 2017;7:3036.
Dimitrov L, et al. Germline Gene Editing in Chickens by Efficient CRISPR-Mediated Homologous Recombination in Primordial Germ Cells. PLoS ONE. 2016;11: e0154303.
Shin SE, et al. CRISPR/Cas9-Induced Knockout and Knock-in Mutations in Chlamydomonas reinhardtii. Sci Rep. 2016 6:27810.
An L, et al. Efficient Generation of FVII Gene Knockout Mice using CRISPR/Cas9 Nuclease and Truncated Guided RNAs. Sci Rep. 2016;6:25199.