Caliper Electrodes

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Caliper Electrodes

In vivo style reusable electrodes compatible with the ECM 830, Gemini X2, ECM 2001+, and Legacy ECM 2001 Electroporation Systems

Product	Item #		Price
Caliper Electrode , 1.0 cm X 1.0 cm, Brass, Transdermal Delivery Applications	45-0101		View Price
Caliper Electrode, 2.0 cm x 2.0 cm with extra 1.5 cm x 1.5 cm electrodes included, Stainless Steel, Electrochemotherapy Applications	45-0102		View Price

Details

BTX Caliper Electrodes are in vivo style reusable electrodes used for a variety of applications, including drug and gene delivery. The electrodes span the target area and deliver electroporation pulses following injection of the molecule of interest. The electric field introduced by the caliper electrodes cause transient pores to form in the cells of the tissue, allowing uptake of the molecules into the cells.

Caliper electrodes are available in two sizes. Each size consists of a caliper and a pair of electrode plates. The 1.0 x 1.0 cm electrode is used in smaller animals with a smaller tissue surface area, while the 2.0 x 2.0 cm is used to target slightly larger surface areas. The end plates of the electrode may be adjusted by using the black roller mounted on the caliper. They may be cleaned with a mild detergent and sterilized with ethanol or ethylene oxide. Properly maintained caliper electrodes have an unlimited lifetime.

REQUIRED CABLES

Required for connection to ECM 2001+
45-0088	Female/Female Adapter Set for Banana Plug Cables
45-2057 or 45-2058	ECM 2001+ HV Output Cable, 5 ft or 10 ft length
Required for connection to Legacy ECM 2001
45-0088	Female/Female Adapter Set for Banana Plug Cables
45-0083	Coaxial to Banana Plug Cables, Red and Black, 10 ft

USE OF CALIPER ELECTRODES WITH THE GEMINI X2 AND ECM 830 ELECTROPORATION SYSTEMS

Gemini X2 and ECM830 generators connect directly to the Caliper Electrode.

USE OF CALIPER ELECTRODES WITH THE ECM 2001+ ELECTROFUSION & ELECTROPORATION SYSTEM

In this example, the ECM 2001+ generator is connected using the sequence of cables and adapters illustrated below, then connected to the Caliper Electrode.

	+		+
ECM 2001+ System		45-2057 or 45-2058 HV Output Cable		45-0088 Female/Female Adapters + Caliper Electrode

USE OF CALIPER ELECTRODES WITH THE LEGACY ECM 2001 ELECTRO CELL FUSION & ELECTROPORATION SYSTEM

In this example, the Legacy ECM 2001 generator is connected to the electrodes using the sequence of cables and adapters illustrated below, then connected to the caliper electrode. Caliper Electrodes plug directly into ECM 830 and Gemini X2 units.

	+		+
ECM 2001 System		45-0083 Coaxial Cables		45-0088 Female/Female Adapters + Caliper Electrode

Generator Compatibility	ECM 830, ECM 2001 and Gemini X2
Voltage Range	0 to 500 V (depending on electrode gap)
Pulse Length Range	10 µs to 99 ms
Electrode Gap	0.1 to 13 cm
Electrode Dimensions	1 x 1 cm (brass) or 1.5 x 1.5 cm and 2 x 2 cm (stainless steel)

In vivo drug or gene delivery
Transdermal tissue applications
Intact plant applications

Caliper Electrodes User's Manual

Cleaning Electrodes

REFERENCES

1. Prud'Homme et al., Human Gene Therapy, 13: 395-406 (2002).

2. Mir et al., PNAS, 96, 4262-4267 (1999).

3. Mir et al., British Journal of Cancer, 77(12), 2336-2342 (1998).

4. Dev et al., U.S. Patent #5,859,327 Jan 12, 1999.

5. Hartikka et al., Molecular Therapy, 4(5), 407-415 (2001).