Welcome To BTX Online !   

Needle Array Electrodes for AgilePulse In Vivo

More Views


Needle Array Electrodes for AgilePulse In Vivo
Miniature needles designed to provide superior, highly-uniform electric fields in dermal or muscular tissue as part of the AgilePulse in vivo Gene Delivery Electroporation System.
Product Item # Price  
4-Needle Array, 4 mm gap, 2 mm length 47-0040   View Price
4-Needle Array, 4 mm gap, 3 mm length 47-0043   View Price
4-Needle Array, 4 mm gap, 5 mm length 47-0045   View Price
6-Needle Array, 4 mm gap, 2 mm length 47-0050   View Price
6-Needle Array, 6 mm gap, 2 mm length 47-0060   View Price
6-Needle Array, 6 mm gap, 10 mm length 47-0070   View Price
6-Needle Array, 6 mm gap, 12 mm length 47-0080   View Price
6-Needle Array, 6 mm gap, 16 mm length 47-0086   View Price
Needle Array Handle 47-0000   View Price
Login/Register to shop in US only.
All others please Login/Register or contact us for local pricing/quotes.

 

 

Details

AgilePulse Needle Array Electrodes are miniature needles designed to provide superior, highly-uniform electric fields in dermal or muscular tissue as part of the AgilePulse in vivo Gene Delivery Electroporation System. Applications for these electrodes include intra-dermal DNA vaccine research and antibody production, cancer chemotherapy research or intra-muscular gene therapy. The miniature parallel-needle array is inserted directly into the target site for fast, reliable in vivo electroporation. The electric fields produced are the closest approximation of parallel plate electrodes, treating approximately 80% of the target area with 95% of the applied electric field. The Needle Array requires the Needle Array handle which includes the Electrode Connector cable. Several needle lengths and row spacing are available for various intra-dermal or intra-muscular applications. Needle Arrays can be used for up to 500 pulses with proper care and maintenance. 

NEEDLE ARRAY DESIGN

  • Uniform, reliable electric fields
  • Miniature needles minimize tissue trauma
  • Disposable, sterile
  • Medical-grade plastic and surgical steel construction
  • Safety-assured design
  • Multiple configurations and sizes to choose

Use of the AgilePulse HT system (formerly Cyto LVT-P) is subject to an annual license agreement between Cellectis bioresearch and the purchaser. Please contact Cellectis bioresearch cytopulse@cellectis.com for further details.

Use of the AgilePulse In Vivo system (formerly the DermaVax device) is not authorized for any veterinary and human therapeutic uses. Contact Cellectis therapeutics contact@cellectis-therapeutics.com for such uses.

INTRA DERMAL NEEDLE ARRAYS

Item # 47-0040 47-0043 47-0045 47-0050 47-0060
Needle Material Stainless Steel Stainless Steel Stainless Steel Stainless Steel Stainless Steel
Needle Tip Fine Point Fine Point Fine Point Fine Point Fine Point
Spacing in Row 1.5 mm 1.5 mm 1.5 mm 1.5 mm 1.5 mm
Spacing Between Rows 4 mm 4 mm 4 mm 4 mm 4 mm
Needles per Row 4 3 4 6 6
Needle Diameter 0.3 mm 0.3 mm 0.3 mm 0.3 mm 0.3 mm
Needle Length 2 mm 3 mm 5 mm 2 mm 5 mm

 

INTRA MUSCULAR NEEDLE ARRAYS

Item # 47-0070 47-0080 47-0086
Needle Material Stainless Steel Stainless Steel Stainless Steel
Needle Tip Fine Point Trocar Point Trocar Point
Spacing in Row 1.5 mm 1.5 mm 1.5 mm
Spacing Between Rows 6 mm 6 mm 6 mm
Needles per Row 6 6 6
Needle Diameter 0.3 mm 0.7 mm 0.7 mm
Needle Length 10 mm 25 mm 16 mm
  • DNA Vaccine Delivery
  • Cancer Vaccine Research
  • Intra-dermal Transfection
  • Gene Therapy Research
  • Intra-muscular Gene Delivery
  • Chemotherapeutic Research

AgilePulse Electrodes User's Manual

 

AgilePulse Electrodes Technical Specifications

 

Cleaning Electrodes

 

REFERENCES

 

Lundberg K, Roos A-K, Pavlenko M, Wehrum D, Pisa P. Peptide specificity of HLA-A2-restricted CD8+ T cell responses induced with DNA vaccines coding for human and rhesus PSA. Vaccine. 2009 Mar 4;27(10):1557-65. Epub 2009. Jan 24 Br

 

Bråve A, Hallengärd D, Gudmundsdotter L, Stout R, Walters R, Wahren B, Hallermalm K. Late administration of plasmid DNA by intradermal electroporation efficiently boosts DNA-primed T and B cell responses to carcinoembryonic antigen. Vaccine. 2009 Jun 8;27(28):3692-6. Epub 2009 May 3.

 

Roos, A-K, Eriksson, F, Walters, D, Pisa, P, King, A. Optimization of skin electroporation in mice to increase tolerability of DNA vaccine delivery to patients. Molecular Therapy, 2009 Sep;17(9):1637-42. Epub 2009 Jun 16.

 

Lladser A, Ljungberg K, Tufvesson H, Tazzari M, Roos A, Quest FG, Kiessling R. Intradermal electroporation with a survivin DNA vaccine induces CTLs against a self-epitope, suppresses angiogenesis and confers long-term protection against mouse.